دانلود مقاله با موضوع ترانگزامیک اسید در گوش و حلق و بینی e A بررسی معاصر
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موضوع به انگلیسی:Tranexamic acid in otorhinolaryngology e A
contemporary review
بخشی از متن:Abstract Tranexamic acid (TXA) is an anti-fibrinolytic agent which has been proven beneficial
in multiple surgical specialties where significant bleeding can occur. Whilst it has been
widely available for over 40 years its use within Otorhinolaryngology is still limited. Operations
in Otorhinolaryngology are particularly varied with some such as tonsillectomy having the potential
for significant life threatening bleeding. Other operations are performed within small
confined surgical fields and even small amounts of bleeding can significantly detriment surgical
field and increase technical difficulty and operative time. This review evaluated the current
literature on the benefits of tranexamic acid within the field of Otorhinolaryngology and Head
and Neck Surgery. Overall TXA was demonstrated to be a safe drug with no major adverse effects
including thromboembolic events reported in any study. It has been shown to be of
particular benefit in rhinology by improving surgical field, reducing operative time and
reducing postoperative swelling and ecchymosis. The benefit in tonsillectomy is less clear
and further studies are required to evaluate its potential use in the reduction of post tonsillectomy
haemorrhage rates
