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موضوع انگلیسی:How Relevant is the Systemic Oxytocin Concentration for Human
Sexual Behavior? A Systematic Review

بخشی از متن:Despite its role in social cognition and affiliative behavior, less is known about the role played by
oxytocin in human sexual behavior.
Aim: In the present systematic review, we aimed to find the levels of oxytocin related to human sexual arousal
and orgasm.
Methods: We conducted the study according to the PRISMA (Preferred Reporting Items for Systematic Reviews
and Meta-Analyses) guidelines. We performed a systematic search in the principal databases for studies that
reported collection of salivary or plasmatic samples, with dosage of oxytocin in relation to sexual activity during
induction of sexual arousal and orgasm.
Results: 414 articles were obtained. After duplicates removal and the application of pre exclusion criteria, 16
articles were considered eligible and 13 articles were included with a Cohen’s k of 0.827. Most of the studies
used sexual self-stimulation and collected plasmatic or salivary samples to measure oxytocin. The sexual arousal
and orgasm were assessed based on subjective reports.
Main Outcome Measure: The primary outcomes were the oxytocin levels collected during the induction of sexual
arousal and orgasm.
Conclusions: Several studies collected only subjective reports about the sexual arousal and the orgasm. Most of
the studies found higher levels of oxytocin during the orgasm or ejaculation. Given the sexual arousal evoked by
self-stimulation in which sexual fantasies play an important role, it should be possible to postulate for a role of
the oxytocin in sexual desire. In particular, we hypothesize a complex role of the oxytocin in the modulation of
sexual fantasies and thoughts that are relevant in the sexual desire and help to trigger genital and sexual arousal.
Cera N, Vargas-Caceres S, Oliveira C, et al. How Relevant is the Systemic Oxytocin Concentration for
Human Sexual Behavior? A Systematic Review. Sex Med 2021;9:100370.


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