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موضوع انگلیسی:Vestibular Mucosa Thickness Measured by Ultrasound in Patients
Affected by Vestibulodynia
بخشی از متن:A multifactorial etiology has been implicated in the development and maintenance of vestibulodynia
(VBD), and atrophic changes of the vestibular mucosa have been observed in many patients.
Aim: To assess the vestibular mucosa thickness in patients with VBD by comparing this sample with a control
group of healthy fertile women and postmenopausal patients with symptoms of genitourinary syndrome of
menopause (GSM).
Methods: Vestibular mucosa thickness was measured with a 20 MHz ultrasound probe (DermaScan C, Cortex
Technology, Denmark), including both the epidermis and dermis.
Main outcome measures: All women were evaluated by anamnesis, physical examination, and self-report
symptoms. Thickness of the vestibular mucosa (expressed in micrometers) was determined by the B-mode,
excluding the hyperechogenic entrance echo and hypoechogenic subcutis. Clinical data related to VBD and GSM
were recorded using a 0- to 10-point visual analog scale related to dyspareunia and vulvar pain/burning (0 ¼ no
pain; 10 ¼ worst possible pain).
Results: A total of 85 patients were recruited: 24 with VBD, 20 with GSM-related symptoms, and 20 matched
controls. Vestibular mucosa thickness measurements were not significantly different between the VBD
(mean ± DS: 1,092.5 ± 226.1 mm) and GSM groups (1,059.7 ± 221.5 mm), while the parameter was
significantly lower (P < .01) than the control group (1,310.6 ± 250.0 mm). Correlation analysis in the VBD and
GSM groups between low vestibular mucosa thickness and symptom intensity (burning/pain and dyspareunia)
showed a significant correlation