دانلود مقاله با موضوع طراحی، سنتز و کاربرد پروب فلوروژنیک برای تشخیص ال-آسپارژیناز در نمونه های سرم
در قالب pdf و در 6 اسلاید،قابل ویرایش، شامل:
موضوع به انگلیسی:Design, synthesis and application of fluorogenic probe for detecting
L-asparaginase in serum samples
بخشی از متن:Fluorescence‐based in vitro assays are highly sensitive, selective and convenient to use, which is suitable for
qualitative and quantitative detection of various types of biological samples. Herein, we designed and synthesized
a novel fluorogenic probe TPAN‐Asn for in vitro L‐asparaginase detection. TPAN‐Asn exhibited selective
and robust response to L‐asparaginase over various anions, cations and amino acids. More importantly, we have
demonstrated that TPAN‐Asn is able to accurately quantify the amount of L‐asparaginase in patient serum samples.
These results suggest that TPAN‐Asn holds great potential in the benchmarking and analysis of Lasparaginase‐
based cancer therapy
