دانلود مقاله با موضوع سنتز مکانیکی شیمیایی برخی از مولکول های هتروسیکلیک
در قالب pdf و در 7 اسلاید،قابل ویرایش، شامل:
موضوع به انگلیسی:Mechanochemical synthesis of some heterocyclic molecules using
Sonogashira cross-coupling reaction and their anticancer activities
بخشی از متن:A greener strategy for the synthesis of some functionalized heterocycles have been developed using Sonogashira
cross-coupling reaction of furfural derived isoxazolidine and isoxazoline derivatives. This is a new approach for
the functionalization of isoxazolidine and isoxazoline derivatives to modified heterocycles via cross-coupling reaction
in solvent free ball-milling process. Since this kind of functionalization of cycloadducts tomodified heterocycles
via cross-coupling reaction are not known in literature, therefore, this approach will surely attract
synthetic chemists to plan for this kind of reactions in organic synthesis. Significant anticancer activity of the
new molecules added extra flavour in this synthesis. Simple reaction methodology, good to excellent yields
and greener approaches are the important features noticed in this syntheses
